Product glycoprofile can be tracked to select quality attributes of cells, product and/or bioprocesses and construct the best manufacturing flowchart
Glycopaneling to maximize cell line development
Glycosylation is governed by cell metabolism at all steps: it reflects the coordinated action of more than a hundred of synthetic enzymes on both the product and host cell proteins.
Glycomonitoring to optimize antibodies, biologics and biosimilars
Glycomonitoring helps selecting quality attributes during cell line management,
clone optimization, scale up and production runs
Monitoring glycosylation patterns during media/ feed screening
delivers high quality attributes and process parameters
Glycomonitoring for gene and cell therapies
→ Cell line expansion
• Stem cells
• CAR-T cells
→ Viral production
